841.Which is an ester local anaesthetic
A.Tetracaine
B.Lignocaine
C.Bupivicaine
D.Etidocaine
E.Prilocaine

842.Which causes methaemoglobinaemia
A.mepivacaine
B.etidocaine
C.prilocaine
D.benzocaine
E.procaine

843.Regarding SSRIs
A.they are safe in OD due to minimal drug interactions
B.serotonin syndrome = hyperthermia and weak muscles
C.they can cause malignant hyperpyrexia
D.OD may cause seizures
E.They are readily removed by dialysis

844.Local anaesthetics
A.Primarily block calcium channels
B.Include the amide procaine
C.Are weak acids
D.Bind to intracellular channel sites
E.Block large nerve fibres at lower doses than small nerve fibres

845.Lithium
A.has a rapid onset of action
B.is partly renally excreted
C.tremor is not a frequent adverse effect
D.has no interactions with NSAIDS
E.is contra-indicated in SSS

846.SSRIs
A.Are structurally similar to TCA
B.Have short half lives
C.Are safe in combination with MAOI
D.Are more effective antidepressants than TCA
E.Can produce decreased libido and decreased sexual function

847.Non depolarizing muscle relaxants
A.Have a limited volume of distribution, which approximates blood volume
B.Are eliminated primarily by liver metabolism
C.Are isoquinolone derivatives
D.Produce a sustained response to titanic stimulus
E.Have a rapid onset of action

848.Haloperidol
A.is excreted mostly via the bile in a conjugated form
B.is 40% protein bound
C.is metabolized in the liver via phosphorylation
D.is a potent DA receptor antagonist
E.has neuroleptic malignant syndrome as a serious adverse effect

849.Thiopentone
A.has low lipid solubility
B.may worsen cerebral oedema
C.has effects on the brain that are terminated by redistribution
D.is not significantly metabolized
E.is likely to increase mean arterial pressure

850.Carbamazepine
A.can be used in the treatment of bipolar disorder, V neuralgia and epilepsy
B.like phenytoin, enhances GABA activity at therapeutic concentrations
C.has a rate of absorption which does not vary widely among different patients
D.can cause a mild but persistent leucopenia and this is an indication to stop treatment
E.has liver enzyme inducing properties

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