671.heparin induced mild thrombocytopenia is caused by
A.release of lipoprotein lipase
B.aggregation
C.thrombosis
D.anitplatelet antibodies
E.none of the above

672.Which is not true of warfarin?
A.It has a half life of 6 hours
B.It is reversed by FFP
C.It is 99% protein bound
D.It affects K synthesis
E.It is 100% bioavailable

673.Which drugs increase the INR
A.Benzodiazepines
B.Barbiturates
C.Rigampicin
D.Cholestyramine
E.Amiodarone

674.Regarding fibrinolytic
A.All thrombolytics act to convert free plasminogen to plasmin
B.Urokinase is a human product
C.tPA and APSAC lack the streptococcal Ag
D.reactions to tPA and anistreplase are preparation related
E.tPA does not occur naturally

675.Regarding heparin
A.Dose reduction is necessary in the elderly
B.LMW fractions have more effect on thrombin than HMW
C.It may cause alopecia
D.It inhibits AT III
E.Protamine is a competitive antagonist

676.which is false about propranolol
A.lipid soluble
B.local anaesthetic action
C.half life 3-6 hours
D.beta sympathetic selectivity
E.30% bioavailable

677.Which has class III antiarrhythmic properties?
A.Adenosine
B.Digoxin
C.Amiodarone
D.Lignocaine
E.Phenytoin

678.captopril
A.has 95% oral bioavailability
B.absorption is enhanced if taken with food
C.is 90% excreted unchanged in urine
D.is acceptable to be given in the 2nd/3rdtrimester pregnancy
E.can cause hypokalaemia

679.atenolol
A.is a β2selective antagonist
B.has 90% oral bioavailability
C.t1/2= 12 h
D.is mostly excreted unchanged in urine
E.its cardiac effects cannot be reversed with atropine

680.dobutamine
A.has its main action as a β2selective agonist
B.decreases systemic and pulmonary resistance
C.can be given orally
D.increases left ventricular filling pressure
E.decreases ventricular ectopics

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