681.verapamil
A.is a dihydropyridine
B.produces more vasodilation than other Ca channel blockers
C.is not effective for use in SVT
D.has diarrhea as an important side effect
E.blocks voltage dependent L type Ca channels

682.verapamil
A.is not hepatically metabolized
B.can cause VF
C.re-entrant SVT is not an indication
D.is less antiarrhythmic than nifedipine
E.is a class III antiarrhythmic

683.thrombolytic therapy is indicated in patients with chest pain who have
A.ST depression
B.ST elevation ot LBBB
C.Non Q –MI
D.Normal ECG
E.None of the above

684.aspirin inhibits the following except
A.COX
B.Recurrent miscarriages
C.PG synthesis
D.Kallikrein synthesis
E.Lipoxygenase

685.Ca channel blockers
A.Cause smooth muscle contraction
B.Have positive inotropic effect
C.Reduce preload significantly
D.Block transmitter gated Ca channels
E.Include dihydropyridines

686.Adenosine is used for
A.AF
B.Atrial flutter
C.VT
D.Sinus bradycardia
E.SVT

687.During warfarin therapy, INR tends to increase with
A.Cholestyramine
B.Vitamin K
C.Metronidazole
D.Rifampicin
E.Phenobarbital

688.Regarding β blockers
A.In clinical use, most are partial agonists
B.Propranolol has minimal 1stpass metabolism
C.βblockers antagonize the release of renin
D.blockage of β2receptors decrease airway resistance
E.metoprolol is a non selective β blocker

689.The half life of Amiodaroneis
A.1-3 minutes
B.1-3 hours
C.4-11 days
D.10-103 days
E.4-6 months

690.regarding nitrates
A.ISMN has a bioavailability of 100%
B.GTN causes platelet aggregation
C.GTN has its primary effect on arterial smooth muscle
D.Methaemoglobinaemia occurs in adults with large doses of nitrates, causing significant clinical effects
E.Nitrates cause bradycardia due to the direct cardiac effects on CGMP levels in myocytes

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