821.The most reliable indication of stage III anaesthesia is
A.Inhibition of reflexes
B.Loss of consciousness
C.Loss of eyelash reflex
D.Irregular respiration
E.Struggling

822.An early sign of local anaesthetic toxicity is
A.Tongue numbness
B.Light headedness
C.Sleepiness
D.Seizures
E.nystagmus

823.In regards to succinylcholine
A.Phase I is augmented by non-depolarising blockers
B.Phase II involves fasciculations
C.Neostigmine is antagonistic in phase I
D.Phase II is similar to non-depolarising blockade
E.Recovery is longer from phase I

824.the following drugs are helpful in Parkinson’sexcept
A.MAO-I
B.D2agonists
C.Antimuscarinics
D.Carbidopa
E.DA reuptake inhibitors

825.The following antipsychotic has the highest sedative and hypotensive action
A.Haloperidol
B.Chlorpromazine
C.Clozapine
D.Thioxanthene
E.Resperidone

826.The most EPS toxicity is with
A.Chlorpromazine
B.Thioxanthene
C.Haloperidol
D.Risperidone
E.Olanzapine

827.TCA
A.Have a low volume of distribution
B.Are useful in urinary retention and chronic pain
C.Can prolong QT interval
D.Block the enzyme which degrades amine neurotransmitters
E.Is useful in severe depression with strong suicidal ideation

828.Diazepam
A.Has no active metabolites
B.Activated charcoal is useful in OD
C.It undergoes extensive enterohepatic recirculation
D.It is a GABA antagonist via the benzodiazepine receptor
E.It has no spinal inhibitory action

829.Atropine
A.Can cause Bronchodilation
B.Produces miosis
C.Is not lipid soluble
D.Blocks reuptake of ACh
E.Causes an increase in salivary gland secretions

830.Regarding inhaled anaesthetics
A.Nitrous oxide has a relatively low minimum alveolar concentration
B.Halogenated agents have a lower brain:blood partition coefficient
C.They reduce mean arterial pressure in direct proportion to their alveolar concentration
D.Nitrous oxide causes a decrease in tidal volume and an increase in respiratory rate
E.They decrease the metabolic rate in the brain by decreasing cerebral blood flow

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