711.SNIP
A.Increases cGMP by release of NO
B.Decreases vascular resistance but increases BP
C.Is a complex of calcium and cyanide groups
D.Is predominantly an arteriodilator
E.Has its onset in 10-15 minutes

712.the most lipid soluble β blocker is
A.propranolol
B.metoprolol
C.atenolol
D.pindolol
E.sotalol

713.All of the following may increase the effect of digoxin except
A.Amiodarone
B.Frusemide
C.Carbamazepine
D.Verapmil
E.Quinidine

714.streptokinase
A.is a complex LPS
B.is synthesised in thehuman kidney
C.binds to the proactivator plasminogen
D.activates plasminogen that is bound to fibrin
E.is more dangerous than t-PA in over 75yos

715.vitamin B12
A.produces anaphylactoid reactions in bolus IV dosing
B.is a treatment for cyanide poisoning
C.is typically given in a dose of 500-1000mg
D.deficiency is caused by renal dialysis
E.is absorbed in the stomach by parietal cells

716.All of the following are known to potentiate oral anticoagulants except
A.Cimetidine
B.Ceftriaxone
C.Reifampicin
D.Metronidazole
E.Trimethoprim/sulfamethoxazole

717.By limiting liver blood flow, cardiac disease may inhibit the metabolism of all of the following except
A.Verapamil
B.Labetalol
C.Propoxyphene
D.Lignocaine
E.Trimethoprim

718.Losartan differs from enalapril in
A.Its selective action on angiotensin type one receptors
B.Its enhanced effect on bradykinin metabolism
C.Its prolonged half life
D.Its higher incidence of drug related angio-oedema
E.Its increased risk of cough

719.all of the following antihypertensives act directly on vascular smooth muscle except
A.felodipine
B.prazosin
C.nitroprusside
D.indapamide
E.hydralazine

720.The toxic effect of organic nitrates include
A.Bradycardia
B.Cyanide poisoning
C.Methaemoglobinaemia
D.Precipitating glaucoma
E.Bronchospasm

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