701.Ca channel blockers affect all the following systems except
A.Skeletal muscle
B.Smooth muscle
C.Brain
D.Pancreas
E.Cardiac muscle

702.Regarding hydralazine
A.It dilates veins more than arterioles
B.It is not orally active
C.It does not undergo first-pass metabolism
D.It may cause compensatory tachycardia and sodium/water retention
E.It may cause hypertrichosis

703.which vasodilator is not administered orally
A.amlodipine
B.minoxidil
C.hydralazine
D.nimodipine
E.diazoxide

704.Regarding SNIP which is false
A.Cyanide is liberated in vascularsmooth muscle cells
B.Decreases afterload in cardiac failure
C.Activates guanylyl cyclase
D.It is light sensitive in aqueous solution
E.Its effects disappear within 10 minutes of discontinutation

705.regarding clonidine, which is false
A.rebound hypertension may occur with 1 or 2 missed doses
B.useful in treatment of tobacco and opioid withdrawal
C.naloxone can be used in the management of an OD
D.is a selective α2 agonist in the medulla
E.allows medullary vasomotor centres to respond to Baroreceptor input

706.Which of the following does not increase the likelihood of bleeding in a patient taking Warfarin
A.Aspirin
B.Indomethacin
C.3rdgeneration cephalosporins
D.cimetidine
E.metronidazole

707.The volume of distribution for aspirin at normal doses in a 50kg female averages
A.1L
B.2.5L
C.5.5L
D.8.5L
E.25L

708.An example of an ADH antagonist is
A.ETOH
B.Amiloride
C.Lithium
D.Aldosterone
E.Triamterene

709.carbonic anhydrase inhibitors
A.were developed from early antibiotics
B.are closely related to thiazide diuretics
C.cause metabolic acidosis
D.decrease the pH of the CSF
E.all of the above

710.the Ca channel blocker with the most rapid onset of action when given orally is
A.diltiazem
B.nifedipine
C.verapamil
D.felodipine
E.nicardipine

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