721.Calculate the half life of digoxin in a patient with the renal clearance of 8.4L/h and Vd 5L/kg in a 70 kg man
A.8 h
B.14 h
C.29 h
D.36 h
E.44 h

722.Heparin (2 CORRECT)
A.Dose reduction is necessary in the elderly
B.LMW fractions have more effect on thrombin the HMWH
C.It may cause alopecia
D.It inhibits AT III
E.Inhibits the action of protein C

723.Regarding fibrinolytics
A.TIMI trial showed increased incidence of GI bleed as the major side effect of administration
B.Aminocaproic acid inhibits fibrinolysis

724.diazoxide, which is false
A.is used to treat severe hypertension
B.acts by direct smooth muscle relaxation
C.causes salt and water retention
D.diuretic action
E.is a thiazide derivative

725.hydralazine
A.causes an abrupt but transient fall in BP
B.displays a biphasic BP response

726.THC is
A.Delta-9-tetrahydrocannabinol
B.Tri-hydro-cannabinol
C.Tri-hexa-cannabinate
D.Cis-5-tetrahydrocannabinate
E.Obtained from poppy leaves

727.Heavy marijuana use is not associated with
A.foetal abnormalities
B.raised intraocular pressure
C.chronic bronchitis
D.increased incidence of accidental death
E.depressed humoral immunity

728.‘Crack’ is
A.cocaine hydrochloride
B.cocaine
C.normally swallowed
D.less potent than cocaine powder
E.not teratogenic

729.Which of the following does not contribute to the pharmacologic effects of cocaine
A.Inhibition of NA reuptake
B.Inhibition of DA reuptake
C.Inhibition of 5-HT reuptake
D.Increased NA synthesis
E.Increased 5-HT synthesis

730.hyperactivity, chest pain and hypertension in a 30yo male is most likely due to
A.marijuana intoxication
B.alcohol intoxication
C.Broncos failure to make the finals
D.Cocaine intoxication
E.Mushroom poisoning

NOTE
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