611.Amantadine
A.Is an antiviral drug
B.Produces insomnia not sedation
C.Causes acute psychosis
D.Potentiates DAergic function
E.All of the above

612.A patient with impetigo is most likely going to respond to
A.Phenoxymethylpenicllin
B.Streptomycin
C.Cephalexin
D.Kanamycin
E.Metronidazole

613.The antiviral drug that acts on reverse transcriptase is
A.Acyclovir
B.Zidovudine
C.Gancyclovir
D.Vidarubine
E.All of the above

614.The β-lactam ring is present in all of the following classes of antibiotics except
A.Penicillins
B.Monobactams
C.Fluoroquinolones
D.Carbapenems
E.Cephalosporins

615.The cephalosporinwith the highest activity against Gram +ve is
A.Cefuroxime
B.Cefotaxime
C.Cefaclor
D.Cefepime
E.Cephalothin

616.Macrolide antibiotics
A.are usually active against Neisseria spp
B.are bacteristatic but not bactericidal
C.bind at the 30S ribosomal subunit
D.are unaffected by plasmid mediated resistance
E.enhance metabolism by cytochrome P450 pathways

617.Metronidazole
A.inhibits alcohol dehydrogenase
B.is effective for vaginal trichomoniasis
C.does not cause a metallic taste in the mouth
D.turns urine green

618.Penicillin reach high concentrations in
A.Vitreous humour
B.CSF with normal meninges
C.Proximal tubulular fluid of the kidney

619.Zidovudine (AZT)
A.Has a short half life
B.Inhibits viral thymidine kinase
C.Has no activity against retroviruses

620.Acyclovir
A.is commonly given in doses of 10-20mg tds
B.is used to treat CMV
C.is a guanosine analogue
D.acts to inhibit viral entry into cells
E.is only available IV

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