611.Amantadine
A.Is an antiviral drug
B.Produces insomnia not sedation
C.Causes acute psychosis
D.Potentiates DAergic function
E.All of the above
612.A patient with impetigo is most likely going to respond to
A.Phenoxymethylpenicllin
B.Streptomycin
C.Cephalexin
D.Kanamycin
E.Metronidazole
613.The antiviral drug that acts on reverse transcriptase is
A.Acyclovir
B.Zidovudine
C.Gancyclovir
D.Vidarubine
E.All of the above
614.The β-lactam ring is present in all of the following classes of antibiotics except
A.Penicillins
B.Monobactams
C.Fluoroquinolones
D.Carbapenems
E.Cephalosporins
615.The cephalosporinwith the highest activity against Gram +ve is
A.Cefuroxime
B.Cefotaxime
C.Cefaclor
D.Cefepime
E.Cephalothin
616.Macrolide antibiotics
A.are usually active against Neisseria spp
B.are bacteristatic but not bactericidal
C.bind at the 30S ribosomal subunit
D.are unaffected by plasmid mediated resistance
E.enhance metabolism by cytochrome P450 pathways
617.Metronidazole
A.inhibits alcohol dehydrogenase
B.is effective for vaginal trichomoniasis
C.does not cause a metallic taste in the mouth
D.turns urine green
618.Penicillin reach high concentrations in
A.Vitreous humour
B.CSF with normal meninges
C.Proximal tubulular fluid of the kidney
619.Zidovudine (AZT)
A.Has a short half life
B.Inhibits viral thymidine kinase
C.Has no activity against retroviruses
620.Acyclovir
A.is commonly given in doses of 10-20mg tds
B.is used to treat CMV
C.is a guanosine analogue
D.acts to inhibit viral entry into cells
E.is only available IV