1761. An anephlerotic reaction which sustains the availability of oxaloacetate is the carboxylation of :

A. Glutamate
B. Pyruvate *
C. Citrate
D. Succinate

1762. The following compounds are intermediate of Tricarboxylic acid (TCA) cycle except :

A. Malate
B. Pyruvate *
C. Oxaloacetate
D. Fumarate

1763. Lactate production is increased in what conditions :

A. Septic shock
B. Cancer
C. Exercise
D. All of the above *

1764. Glucose is the only source of energy for :

A. Myocardium
B. Kidneys
C. Erythrocytes *
D. Muscles

1765. Glycogen synthase is activated by :

A. Phosphorylation
B. Adenylation
C. Dephosphorylation *
D. Deadenylation

1766. Glycolysis is the ____:

A. Conversion of pyruvate to lactate
B. Conversion of pyruvate to Acetyl CoA
C. Conversion of pyruvate to glucose
D. Conversion of glucose to pyruvate /Lactate *

1767. The synthesis of 2,3-Bisphosphoglycerate occurs in :

A. Brain
B. Muscles
C. Liver
D. Erythrocytes *

1768. Pyruvate dehydrogenase complex and ot-ketoglutarate dehydrogenase complex require the following for their oxidative decarboxylation :

A. CoASH and lipoic acid
B. NAD+ and NAD
C. CoASH and TPP
D. CoASH , TPP , NAD+ , FAD, Lipoate *

1769. Von Gierke’s disease is characterized by a deficiency of :

A. Glucokinase
B. Glucose 6 phosphatase *
C. Alpha 1-6 glucosidase
D. Glycogen synthase

1770. Pyruvate dehydrogenase is inhibited by :

A. Oxidized lipoamide
B. PDH Kinase
C. Acetyl CoA and NADH *
D. Oxaloacetate