1701. The name of the construction that makes amalgamation of RNA stop is known as the :
A. Promoter region
B. Sigma factor
C. Transcription terminator *
D. Polymerase
E. Template
1702. One code word for glutamate is GAG, and a code word for valine is GUG and the mutation in sickle cell disease is this codon, the kind of mutation is :
A. Deletion
B. Insertion
C. Nonsense mutation
D. Transition
E. Transversion *
1703. Anticodons are present on :
A. Coding strand of DNA
B. mRNA
C. tRNA *
D. rRNA
1704. Which of the following statements best describes the relationship between the nucleotide sequences of the template strand and the non template strand in the DNA of a gene ?
A. They are compatible with one another *
B. They are covalently attached to each other
C. The are identical to each other
D. The are parallel to each other
E. U in the coding strand is found in place of the T in the non-coding stand
1705. Which of the following is the initiating code ?
A. AUG *
B. CCA
C. CCU
D. UCA
E. UGA
1706. All of the following compounds directly provide carbon and nitrogen atoms to form purine ring except :
A. Aspartate
B. Carbamyl phosphate *
C. CO2
D. Glutamine
E. Glycine
1707. Lesch-Nyhan syndrome is due to deficiency of :
A. Hypoxanthine-guanine phosphoribosyl-transferase (HGPRT) *
B. Phosphoribosyl pyrophosphate (prpp) synthase
C. Carbamoyl phosphate synthase I
D. Xanthine oxidase
E. Arginase
1708. During replication, DNA fragments are sealed by :
A. DNA polymerase II
B. DNA Ligase *
C. DNA gyrase
D. DNA Topoisomerase II
E. Helicase
1709. Absolute abs cense of hypoxanthine guanine phosphoribosyl transferase leads to :
A. Primary gout
B. Lesh-Nyhan syndrome *
C. Orotic aciduria
D. Dwarfism
E. Immunodeficiency syndrome
1710. A patient, with classic symptoms of gouty arthritis , was treated with Allopurinol. Allopurinol inhibits the conversion of :
A. Adenine to guanine
B. Adenine to Hypoxanthine
C. Hypoxanthine to IMP
D. Hypoxanthine to Xanthine *
E. IMP to AMP