1661. The end of purine catabolism in man is :
A. Inosine
B. Hypoxanthine
C. Xanhine
D. Uric acid *
E. Urea
1662. DNA Fragments are sealed by :
A. DNA polymerase II
B. DNA Ligase *
C. DNA Gyrase
D. DNA Topoisomerase II
E. None of the above
1663. Hypouricemia can occur in :
A. Deficiency of ribonucleotide reductase
B. G-6 Phosphate deficiency
C. HGPRT Deficiency
D. Leukaemia
E. Xanthine oxidase deficiency *
1664. Lesch-Nyhan syndrome is due to deficiency of :
A. Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) *
B. Phosphoribosyl pyrophosphate (PRPP)
C. Carbamoyl phosphate
D. Xanthine oxidase
E. Arginase
1665. Purine catabolism in humans results in:
A. Hypoxanthine
B. Urea
C. Uric acid *
D. Inosine
E. Xanthine
1666. In man chief catabolic product of pyrimidines is :
A. Beta-Alanine *
B. Allantion
C. Hypoxanthine
D. Urea
E. Uric acid
1667. The pyrimidine ring’s two nitrogen are provided by:
A. Ammonia and glycine
B. Aspirate and carbamoyl phosphate
C. Glutamine and ammonia
D. Aspartate and ammonia *
E. Aspartate and glycine
1668. Which of the following amino acids contributes both carbons and nitrogen atoms for purine synthesis ?
A. Glutamine
B. Glycine *
C. Glutamate
D. Cysteine
E. Lysine
1669. The initiation site of transcription is recognized by :
A. Alpha subunit of DNA dependent RNA Polymerase
B. Beta subunit of DNA dependent RNA Polymerase
C. Sigma factor*
D. RHO factor
E. None of the above
1670. Non coding sequences in a gene are known as :
A. Anticodons
B. Cistrons
C. Exons
D. Introns *
E. None sense codons