1751. Muscle glycogen cannot contribute directly to blood glucose level because of :

A. Muscle glycogen cannot be converted to glucose -6- phosphate
B. Muscle lacks glucose -6-phosphate *
C. Muscle contain no glucokinase
D. Muscle contain no glycogen phosphorylase
E. Muscle lacks phosphoglucoisomerase

1752. The activity of which of the following enzymes lead to substrate level phosphorylation in TCA cycle ?

A. Isocitrate dehydrogenase
B. A- Ketoglutarate dehydrogenase
C. Succinate thiokinase *
D. Fumarase
E. Succinate dehydrogenase

1753. Cyclic AMP is formed from ATP by the enzyme adenylate cyclase which is activated by the hormones:

A. Insulin
B. Epinephrine *
C. Testosterone
D. Progesterone
E. Cortisol

1754. Deficiency of enzyme glucose-6- phosphate dehydrogenase will lead to hemolytic anaemia due to :

A. Deficient energy
B. Lack of reduced NADP *
C. Deficiency of glutathione reductase
D. Lack of oxygen
E. All of the above

1755. The connecting link between Hexose Mono-phosphate HMP pathway and lipid synthesis is :

A. Ribose
C. Sedoheptulose 7 phosphate
E. All of them

1756. An enzyme used in both glycolysis and gluconeogenesis is :

A. 3- phosphoglycerate kinase *
B. Glucose-6- phosphatase
C. Hexokinase
D. Phosphofructokinase
E. Pyruvate kinase

1757. A deficiency of which enzyme given below best describes an individual with hypoglycemia, hyperuricemia , hyperlipidemia and lactic acidosis ?

A. Amylo-4 6 glucosidase
B. Amylo 1 6 glucosidase *
C. Glucose -6- phosphatase
D. Glycogen synthase
E. Liver glycogen phosphorylase

1758. An intermediate involved in the synthesis of glycogen is :

A. Fructose -1-phosphate
B. GDP-glucose *
C. UDP-glucose
D. Ribulose -5- phosphate
E. Fructose -1,6 bisphosphate

1759. Lactate that is released into the circulation can be converted back to glucose in :

A. Adipose tissue
B. Brain
C. Erythrocytes
D. Heart Muscle
E. Liver*

1760. Which of the following is a rate limiting enzyme of gluconeogenesis :

A. Hexokinase
B. Phosphofructokinase
C. Pyruvate carboxylase *
D. Pyruvate kinase
E. None of them