611. The following drugs induce chronic hepatitis:
A. methotrexate
B. a methyldopa
C. isoniazid
D. all of the above
E. none of the above 

612. Which of the following statement regarding chronic hepatitis is FALSE?
A. fatty change in the liver is seen in HCV but not in HBV chronic hepatitis
B. cirrhosis takes> 1 Oyears to develop from the onset of viral infection
C. chronic hepatitis is common in acute HBV & HDV co-infection
D. prognosis of chronic hepatitis is ultimately determined by aetiology of hepatitis
E. over 90% of neonates infected with HBV will ultimately develop chronic hepatitis

613. Autoimmune hepatitis is associated with:
A. rheumatoid arthritis
B. Sjogren’s syndrome
C. Ulcerative colitis
D. Autoimmune thyroiditis
E. All of the above

614. In hepatic failure, there is:
A. predominantly unconjugated hyperbilirubinemia
B. fetor hepaticus is not a constant feature
C. reduced factor II, V VII, IX & X is due to vitamin K malabsorption
D. DIC occurs in hepatic failure due to reduction in clotting factors
E. Spider naevi is due to defective urea cycle

615. In hepatic failure, the following occur due to hyperoestrogenism:
A. palmar erythema
B. spider naevi
C. testicular atrophy
D. all of the above
E. none of the above

616. Most common cause of cirrhosis in Western countries is:
A. alcoholic liver disease
B. viral hepatitis
C. hemachromatosis
D. Wilson’s disease
E. Cryptogenic liver disease

617. Which of the following is a DS DNA virus
A. Adenovirus
B. Coronavirus
C. Mumps virus
D. Rotavirus
E. Hepatitis C virus

618. Regarding viral respiratory infections
A. Rhinovirus causes 60% of common colds
B. All respiratory viruses are SSRNA
C. Most prefer temperatures above 37°C
D. They are characterised by neutrophilia
E. Influenza is not a major cause of morbidity or mortality

619. Tuberculosis
A. is decreasing in incidence
B. is able to induce type II hypersensitivity
C. results in the formation of a ghon complex as part of secondary infection
D. is characterised by an intense initial phagocytosis by macrophages
E. is extrapulmonary in most patients with AIDS

620. All of the following invade gut epithelial cells EXCEPT
A. Shigella
B. Campylobacter
C. Rotavirus
D. Vibrio cholerae
E. Salmonella

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