731. In tumor invasion & dissemination:
A. Extracellular matrix cleavage products are growth promoting & chemotactic for tumor cells.
B. Tumor invasion through the extracellular matrix is by progressive expansile growth
C. Tumor cells downregulates their adhesion molecules to reduce adhesion to each other during vascular dissemination
D. Organ selective homing of tumor cells are purely due to the anatomical location of the primary tumor.
E. All of the above
732. Cushing’s syndrome may occur as a paraneoplastic syndrome in:
A. SCC lung
B. Small cell carcinoma of lung
C. Large cell carcinoma of lung
D. Mesothelioma
E. All of the above
733. PTHrP is commonly expressed by:
A. SCC lung
B. Renal cell carcinoma
C. Ovarian carcinoma
D. Adult T cell lymphoma
E. All of the above
734. Which of the following is NOT a paraneoplastic syndrome in bronchogenic carcinoma?
A. Horner’s syndrome
B. Hypercalcemia
C. Hypertrophic pulmonary osteo-arthropathy
D. Clubbing
E. All of the above are paraneoplastic syndrome of bronchogenic carcinoma
735. uFP is increased in the following EXCEPT:
A. Hepatocellular carcinoma
B. Cirrhosis
C. Carcinoma of colon
D. Lactation
E. Bronchogenic carcinoma
736. Most common cause of acute pancreatitis in female is:
A. cholelithiasis
B. ERCP
C. Mycoplasma pneumoniae
D. Oestrogen
E. Trauma
737. Which of the following regarding acute pancreatitis is FALSE?
A. 5% of patients with cholelithiasis develop pancreatitis
B. Trypsin is activated in acute pancreatitis, leading to activation of clotting system & proteolysis of pancreas
C. Calcification of necrosed fatty tissue occurs at pancreas as well as at ectopic sites
D. Elevation of amylase occurs within 2 hours
E. 5% die of shock within 1 week.
738. Complications of acute pancreatitis include:
A. pancreatic pseudocyst
B. duodenal obstruction
C. ARDS
D. Acute renal failure
E. All of the above
739. Most common cause of chronic pancreatitis is”
A. cholelithiasis
B. alcoholism
C. hyperlipidemia
D. hypercalcaemia
E. pancreas divisum
740. l’ risk for carcinoma of pancreas is observed in:
A. acute pancreatitis
B. chronic pancreatitis
C. diabetes mellitus
D. all of the above
E. none of the above