701. Regarding hypersensitivity reactions
A. In anaphylaxis, IgE is bound to mast cells by their Fab portions to release vasoactive ammes
B. Goodpasture’s syndrome is an example of type III hypersensitivity reaction
C. Farmer’s lung is a type III reaction to micropolyspora species
D. Delayed hypersensitivity is mediated by macrophages
E. The Mantoux reaction is a form of contact hypersensitivity

702. Acute appendicitis
A. In preschool children, it usually presents with the so-called “classic” signs and symptoms
B. It is associated with appendiceal obstruction in 10% of cases
C. Histologically, it shows neutrophilic infiltration of the muscularis layer
D. The clinical diagnosis is falsely positive in about 50% of cases
E. It cannot cause liver abscesses

703. Pneumocystis carinii
A. Produces pneumocystis pneumonia in normal persons
B. Causes a Ghon’s focus in the lung
C. Causes patchy atelectasis
D. Is a fungus
E. Attaches selectively to Type II alveolar cells

704. Regarding septic shock
A. Endotoxin is the only cause
B. Marked vasoconstriction occurs in the non-infected tissue
C. Cardiac output is low in 75% of patients
D. Endotoxin entering the circulation causes an effect very similar to anaphylaxis
E. Blood viscosity is unchanged

705. Acute pancreatitis
A. Is associated with increased serum amylase concentration without elevation in serum lipase concentration
B. Occurs most often in later life
C. Occurs in about 5% of patients with gallstones
D. When associated with alcohol is not usually preceded by chronic pancreatitis
E. Is often associated with hypercalcaemia

706. The acute nephritic syndrome has all of the following features except
A. Proteinuria
B. Haematuria
C. Hypertension
D. Hyaline casts
E. Oliguria

707. A young baby presents with jaundice, dark urine and pale stools. He is most likely to have
A. Physiologic jaundice of the newborn
B. Breast milk jaundice
C. Gilbert’s syndrome
D. Biliary atresia
E. None of the above

708. With regard to the leukocyte extravasation of the acute inflammatory response, which of the following is incorrect
A. ELAM-l is a selectin found on endothelium
B. E and P-selectins bind to oligosaccharides found on neutrophils and monocytes
C. L-selectin is found on neutrophils, monocytes and lymphocytes
D. ICAM-l belongs to the immunoglobulin family of molecules, and is found on leukocytes
E. VCAM-l binds to integrins

709. IgE mediated Type I hypersensitivity reactions require the action of which lymphocyte class
A. B only
B. CD8 T cells and B cells
C. T).l2 T cells and B cells
D. T).ll T cells and B cells
E. Natural Killer cells and B cells

710. Thrombus formation is inhibited by
A. Von Willebrands factor
C. Alpha 2 macroglobulin
E. Endothelial cell injury

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