1001.Dystrophic calcification can be caused by
A.Sarcoidosis
B.Multiple myeloma
C.Advanced renal failure
D.Advanced atherosclerosis
E.All of the above

1002.Regarding atrophy and hypertrophy
A.Hypertrophy refers to an increase in the number of cells in an organ or tissue
B.The phenotype of an individual cell may be altered in hypertrophy
C.Atrophy is always pathological
D.In the heart, trophic triggers are the only factors that cause hypertrophy
E.The colour of brown atrophy is due to melanin pigmentation

1003.Cytosolic calcium in cell injury
A.Only enters by active transport
B.Partially derives from mitochondria
C.Increases ATP
D.Inactivates phospholipase
E.Inactivates protease

1004.Metaplasia (2 correct)
A.Is usually a premalignant condition
B.Is due to genetic reprogramming of cells
C.May be regulated byVit B12
D.The most common type is from squamous to columnar epithelium
E.Is irreversible

1005.Hypertrophy
A.Occurs after partial hepatectomy
B.Is triggered by mechanical and trophic chemicals
C.Increases function of an organexponentially
D.Is usually pathological
E.Occurs after denervation

1006.All of the following are morphological features of apoptosis except
A.Cell swelling
B.Chromatin condensation
C.Lack of inflammation
D.Phagocytosis of apoptotic bodies
E.Formation of cytoplasmic blebs

1007.Irreversible cell injury is characterized by
A.Loss offunctional polarity in polarized epithelium
B.Detachment of ribosomes from ER
C.Acute cellular swelling
D.Severe mitochondrial vacuolization
E.Formation of membrane blebs

1008.Features of reversible cell injury include all except
A.Swelling of the cell
B.Clumping of nuclear chromatin
C.Autophagy by lysosomes
D.Nuclear karyorrhexis
E.Ribosomal dispersal

1009.In necrosis
A.The nuclear changes are due to non-specific breakdown of DNA
B.Karyolysis and pyknosis are the only 2 types of nuclear changes
C.In caseous necrosis the basic outline of the cells is preserved
D.There is a decreased eosinophiliain the necrotic cells
E.Liquefaction necrosis is characteristic of hypoxic injury

1010.Regarding atrophy, which is false
A.Persistence of residual bodies
B.Decrease in myofilaments
C.Decreasedrough ER
D.Decreased autophagic vacuoles
E.Decreased smooth ER

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