621. Which of the following regarding insulin receptor is FALSE?
A. It is a steroid receptor
B. It is a tetramer with 2a & 213 glycoprotein subunits linked by disulfide bonds
C. It is similar in structure to IGFI receptors
D. It is endocytosed upon insulin binding & degraded
E. Its number increases in starvation

622. Insulin receptors increase in number with:
A. Obesity
B. Acromegaly
C. Exogenous corticosteroids
D. Adrenal insufficiency
E. All of the above

623. In diabetes mellitus, there is:
A. -.v glucose entry into peripheral tissues
B. l’ hepatic gluconeogenesis
C. -.v amino acid uptake into the cell
D. l’ lipolysis
E. All of the above

624. Which of the following regarding diabetes mellitus is INCORRECT?
A. Glucose uptake by neurones& red cells is normal
B. Glucose resorption from urine is reduced
C. Glycogenolysis is stimulated
D. Hepatic glucose output is facilitated by glucagon & cortisol                                                                                     E. All of the above

625. Uncontrolled diabetes mellitus does NOT:
A. l’ serum osmolality
B. 1’urine sodium & potassium loss
C. negative nitrogen balance
D. -.v circulating lipids
E. l’ circulating lactate

626. Autonomic symptoms in hypoglycemia occurs at blood sugar level of:
A. 6mmol/L
B. 5mmollL
C. 4mmol/L
D. 3 mmol/L
E. 2mmol/L

627. The following symptom of hypoglycemia occurs at the following blood sugar level:
A. Confusion -4 mmollL
B. Coma-1.7 mmol/L
C. Convulsion – 3 mmollL
D. Permanent brain damage – 2 mmol/L
E. All of the above

628. Basal secretion of Insulin occurs at:
A. 1unitlhour
B. 2unitlhour
C. 3 unit/hour
D. 4unitlhour
E. 5unitlhour

629. Average amount of insulin secreted per day is:
A. 10 units/day
B. 20 units/day
C. 30 units/day
D. 40 units/day
E. 50 units/day

630. Insulin release reduces with:
A. Vagal stimulation
B. 13 adrenergic stimulation
C. Hypokalaemia
D. Glucagon
E. None of the above

NOTE
IF YOU THINK ANY OF THE MCQ ABOVE IS WRONG.
PLEASE COMMENT WITH CORRECT ANSWER AND ITS DETAIL EXPLANATION IN COMMENT BOX.
THANK YOU

Leave a Reply